A Scientific
Website of Kardiolab
Cardiovascular risk calculators
initiated by the vascular risk foundation
VARIFO, Olten
SGIM 2009 posters about CRP and comparison of coronary calcium with total plaque are, TPA.
Every body needs a Statin, a study suggests (Jupiter). However, Jupiter raises some questions. Knowledge of your patients CRP might not be likeli to change a risk category. Try it out here on our Reynolds calculator.
You will be astonished: increasing CRP leaves global risk virtually unchanged; further: if you manage to reduce CRP by 50%, e.g. from 4.0 to 2.0, you will have the same risk reduction when you manage to reduce total cholesterol e.g. from 7.0 mmol/l to 6.5 mmol/.
So: all the effect of Statins on risk reduction are mainly driven by the reduction in total cholesterol and of course LDL-Cholesterol.
We instead suggest to treat subjects more aggressively with proven atherosclerosis as evidenced by imaging....
What else does our calculator offer: you can immediately see, if guidelines would recommend an LDL-lowering drug and you can change different risk factors in order to weigh their relative importance to reduce global risk: for myocardial infarction and stroke! Try it out here !
SCOPRI is a scientific website of KARDIOLAB. Among other, it is exhibiting several experimental risk assessment tools that allow you to calculate your patients 10 year risk for vascular events.
Your questions can be addressed to info@kardiolab.ch .
SCOPRI is generated by Michel Romanens and Franz Ackermann.
Thank You for Your visit
Aim:
We are currently seeking for scientific workers who might wish to collaborate with KARDIOLAB.
Scientific Co-Workers and Adivosors are:
Michel Romanens, Olten, MD
Franz Ackermann, Olten, MD
The activities of SCOPRI, KARDIOLAB and VARIFO are payed in part by Michel Romanens, MD, and in part by the Foundation Vascular Risk Prediction VARIFO. Michel Romanens is the President of VARIFO.
We are deeply grateful to the Unigamma Foundation, Aarau, and the Thalmann Foundation, Olten.
Headquarter:
Dr. med. Michel Romanens
Ziegelfeldstrasse 1
CH 4600 Olten
tel 062 212 44 10
fax 062 212 44 30
Background:
SCOPRI was created in 2003 by F. Ackermann and M. Romanens. The website originally featured cardiovascular risk calculators. In 2007 it is transformed to a think tank for physicians and other medical staff that are interested in a scientific collaboration with us. We offer co-authorship for ongoing scientific work and publications.
If you are interested in a collaboration, just send an email.
Our goals are:
1. Improve cardiovascular risk prediction on a scientific base.
2. Perform practice- and population-based cardiovascular risk assessment and outcome studies accepted by ethical committees.
3. Offer free risk assessment tools to subjects who otherwise would be missed to the medical attention on behalf of publicity and advertisements (local radio stations and newspapers), including psychosocial risk stratification tools
Brief News:
20.12.2008: New clinical risk calculator now available (link). It includes PROCAM, SCORE, PROCAM 2007 and REYNOLDS for men and women.
04.12.2008: first TPA Course held in Olten. The scientific and practicle base of TPA link is now well established.
01.11.2008: The Jupiter Trial is published. We were the scientific group who managed and selected the Jupiter Patients in Olten. The real importance of Jupiter for primary prevention of AMI is however debateable. More news on this topic will follow.
Selected scientific activities of SCOPRI and KARDIOLAB in cardiovascular medicine:
Read my Book chapter on Imaging as a Cardioascular Risk Marker (Atherosklerose -Prävention 2007, Editors: E. Battegay, G. Noseda, W.F.Riesen) link
Study on posttest risk calculations.
Cohort study on risk inherent to coronary calcified and carotid plaques
Coordinaton of the National Taskforce on atherosclerosis imaging
Principal Investigator of the Cordicare Programs of the Vascular Risk Foundation
Book about Bayes Theorem and other predictors in medicine
PUBLICATIONS (selected)
risk assessment tools
and guidelines for 10-year
coronary heart disease risk in practice-based primary care (pdf)
risk modifier in primary care patients using predictor models
of the European and international
atherosclerosis societies (pdf)
Agreement of Swiss-Adapted International and European Guidelines for the Assessment of Global Vascular Risk and for Lipid Lowering Interventions January 2009